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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1928 1
1932 1
1941 1
1957 1
1963 1
1965 2
1966 1
1967 1
1968 2
1970 1
1972 4
1973 1
1975 26
1976 23
1977 19
1978 32
1979 31
1980 48
1981 51
1982 51
1983 50
1984 68
1985 90
1986 79
1987 73
1988 112
1989 110
1990 111
1991 126
1992 98
1993 121
1994 134
1995 132
1996 161
1997 151
1998 151
1999 203
2000 146
2001 177
2002 186
2003 195
2004 266
2005 257
2006 282
2007 277
2008 291
2009 313
2010 335
2011 326
2012 358
2013 395
2014 376
2015 377
2016 370
2017 453
2018 471
2019 422
2020 448
2021 524
2022 487
2023 467
2024 203

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Search Results

9,677 results

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Page 1
Designing Hydrogels for On-Demand Therapy.
Oliva N, Conde J, Wang K, Artzi N. Oliva N, et al. Acc Chem Res. 2017 Apr 18;50(4):669-679. doi: 10.1021/acs.accounts.6b00536. Epub 2017 Mar 16. Acc Chem Res. 2017. PMID: 28301139 Free PMC article. Review.
This treatment modality is associated with side effects, off-target accumulation, toxicity, and rapid renal and hepatic clearance. Multiple efforts have focused on incorporating targeting moieties into systemic therapeutic vehicles to enhance retention and minimize clea …
This treatment modality is associated with side effects, off-target accumulation, toxicity, and rapid renal and hepatic clearance. Mu …
High-Flow Nasal Cannula Oxygen Therapy: Physiological Mechanisms and Clinical Applications in Children.
Nolasco S, Manti S, Leonardi S, Vancheri C, Spicuzza L. Nolasco S, et al. Front Med (Lausanne). 2022 Jun 3;9:920549. doi: 10.3389/fmed.2022.920549. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35721052 Free PMC article. Review.
This is undoubtedly due to its ease of use and safety, which allows it to be used in a wide variety of settings, ranging from pediatric intensive care to patients' homes. HFNC devices make it possible to regulate gas flow and temperature, as well as allowing some ne …
This is undoubtedly due to its ease of use and safety, which allows it to be used in a wide variety of settings, ranging from pediatr …
Pharmacokinetic issues for antibiotics in the critically ill patient.
Roberts JA, Lipman J. Roberts JA, et al. Crit Care Med. 2009 Mar;37(3):840-51; quiz 859. doi: 10.1097/CCM.0b013e3181961bff. Crit Care Med. 2009. PMID: 19237886 Review.
., aminoglycosides, beta-lactams, glycopeptides, and colistin) are mostly affected with the pathphysiological changes observed in critically ill patients with increased volumes of distribution and altered drug clearance (related to changes in creatinine clearance). …
., aminoglycosides, beta-lactams, glycopeptides, and colistin) are mostly affected with the pathphysiological changes observed in critically …
Plasma clearance.
Toutain PL, Bousquet-Mélou A. Toutain PL, et al. J Vet Pharmacol Ther. 2004 Dec;27(6):415-25. doi: 10.1111/j.1365-2885.2004.00605.x. J Vet Pharmacol Ther. 2004. PMID: 15601437 Review.
Plasma (total, systemic...) clearance is determined by all the individual metabolizing/eliminating organ clearances and involves mainly liver and kidney clearances. ...Plasma clearance is the most important pharmacokinetic parameter because it is the o …
Plasma (total, systemic...) clearance is determined by all the individual metabolizing/eliminating organ clearances and involv …
Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System.
El-Kattan AF, Varma MVS. El-Kattan AF, et al. Drug Metab Dispos. 2018 May;46(5):729-739. doi: 10.1124/dmd.117.080044. Epub 2018 Mar 1. Drug Metab Dispos. 2018. PMID: 29496721 Review.
An early understanding of the transporter role in drug disposition and clearance allows reliable prediction/evaluation of pharmacokinetics and changes due to drug-drug interactions (DDIs) or genetic polymorphisms. We recently proposed an extended clearance cl …
An early understanding of the transporter role in drug disposition and clearance allows reliable prediction/evaluation of phar …
Does diametrical clearance influence the wear of Pinnacle hip implants?
Bergiers S, Hothi H, Henckel J, Eskelinen A, Skinner J, Hart A. Bergiers S, et al. Bone Joint Res. 2020 Aug 25;9(8):515-523. doi: 10.1302/2046-3758.98.BJR-2019-0195.R2. eCollection 2020 Aug. Bone Joint Res. 2020. PMID: 32922759 Free PMC article.
AIMS: The optimum clearance between the bearing surfaces of hip arthroplasties is unknown. Theoretically, to minimize wear, it is understood that clearances must be low enough to maintain optimal contact pressure and fluid film lubrication, while being large enough …
AIMS: The optimum clearance between the bearing surfaces of hip arthroplasties is unknown. Theoretically, to minimize wear, it is und …
Remifentanil.
Cohen J, Royston D. Cohen J, et al. Curr Opin Crit Care. 2001 Aug;7(4):227-31. doi: 10.1097/00075198-200108000-00003. Curr Opin Crit Care. 2001. PMID: 11571418 Review.
Its metabolism by nonspecific esterases results in rapid and uniform clearance leading to highly predictable onset and offset of action. ...In the cardiac setting, the drug provides excellent intraoperative hemodynamic control while allowing return of spontaneous ve …
Its metabolism by nonspecific esterases results in rapid and uniform clearance leading to highly predictable onset and offset of acti …
Precision medicine in bronchiectasis.
Pembridge T, Chalmers JD. Pembridge T, et al. Breathe (Sheff). 2021 Dec;17(4):210119. doi: 10.1183/20734735.0119-2021. Breathe (Sheff). 2021. PMID: 35035573 Free PMC article. Review.
Patients experience symptoms and exacerbations driven by a combination of impaired mucociliary clearance, airway inflammation and airway infection. Treatment of bronchiectasis aims to enhance airway clearance and to address the underlying causes of inflammation and …
Patients experience symptoms and exacerbations driven by a combination of impaired mucociliary clearance, airway inflammation and air …
ToulGaitViz: a tool for the systematic description of lower limb clearance during the swing phase of hemiparetic gait after stroke. A cohort study.
Montané E, Cormier C, Scandella M, Cangelosi A, Marque P, Moissenet F, Gasq D. Montané E, et al. Eur J Phys Rehabil Med. 2023 Dec;59(6):669-681. doi: 10.23736/S1973-9087.23.07979-0. Epub 2023 Oct 23. Eur J Phys Rehabil Med. 2023. PMID: 37869760 Free PMC article.
Both centimetric and angular values of the clearance were reported as well as their correlations with walking speed. ...ToulGaitViz allows visualization of clearance, segmental shortening and compensation evolution before and after any therapeutic interventio …
Both centimetric and angular values of the clearance were reported as well as their correlations with walking speed. ...ToulGaitViz …
Incremental Hemodialysis - A European Perspective.
Tangvoraphonkchai K, Davenport A. Tangvoraphonkchai K, et al. Semin Dial. 2017 May;30(3):270-276. doi: 10.1111/sdi.12583. Epub 2017 Feb 9. Semin Dial. 2017. PMID: 28185299 Review.
Whereas RRF is monitored prior to commencing hemodialysis, once dialysis is started most centres simply rely on dialyzer urea clearance to determine adequate uremic toxin clearance and disregard the effect of RRF. ...Unfortunately, the 24-hour urine collection for u …
Whereas RRF is monitored prior to commencing hemodialysis, once dialysis is started most centres simply rely on dialyzer urea clearance …
9,677 results